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Data Science Institute
William Hogan, MD, MS

William Hogan, MD, MS

Mary T. and Ted D. Kellner Chair of Data Science; Director, Data Science Institute; Professor, Data Science Institute; Associate Director for Data Science, Mellowes Center for Genomic and Precision Medicine

Locations

  • DSI
  • TBRC C4166

    Secondary Appointment: Department of Medicine

Contact Information

Education

MS, Intelligent Systems, University of Pittsburgh
MD, Medicine, Jefferson Medical College
BS, Pennsylvania State University

Biography

Dr. Hogan is professor and the founding director of the Data Science Institute. He has over 20 years experience in biomedical data science and informatics, including numerous leadership roles and accomplishments in building large-scale infrastructure, creating and implementing public health surveillance systems, developing and disseminating data standards, designing and validating artificial intelligence models, and innovating analysis methods. He has also created graduate programs in biomedical data science and informatics from the ground up, with their PhD graduates moving on to postdoctoral research fellowships and faculty positions at multiple institutions. He has served as research mentor to over 20 junior faculty, postdoctoral research fellows, and MS and PhD students. Over the years, he has been principal investigator or co-investigator on over $100M in grant funding, including major infrastructure grants that include as a core component the transformation of electronic health record data into a research-ready resource for observational and comparative effectiveness studies, pragmatic trials, disease surveillance, and cohort discovery for enrollment in trials. He has authored over 150 peer-reviewed publications describing this work. His core area of interest is biomedical ontology, or how to represent the types of things that are objects of study in healthcare and biomedical science in order to ensure that data are reusable and that information systems are interoperable. He is the creator and lead curator of three, major ontologies in the Open Biological and Biomedical Ontology (OBO) Foundry: the Drug Ontology, the Ontology of Medically Relevant Social Entities, and the Apollo-SV ontology. All three ontologies rank in the top 20% of OBO ontologies in terms of re-use by other OBO ontologies. He serves on the OBO Foundry Operations Committee and its Editorial Working Group.

Publications

  • (Conderino S, Kirchner HL, Thorpe LE, Divers J, Hirsch AG, Nordberg CM, Schwartz BS, Zhang L, Cai B, Rudisill C, Obeid JS, Liese A, Allen KS, Dixon BE, Crume T, Dabelea D, Burgett S, Bellatorre A, Shao H, Bian J, Guo Y, Bost S, Lyu T, Reynolds K, Mefford MT, Zhou H, Zhou M, Lustigova E, Utidjian LH, Maltenfort M, Kamboj M, Mendonca EA, Hanley P, Zaganjor I, Pavkov ME, Rosenman M, Titus AR, DiCAYA Study Group .) J Am Med Inform Assoc. 2026 Mar 01;33(3):710-718 PMID: 41442443 PMCID: PMC12884381 SCOPUS ID: 2-s2.0-105033000578 12/24/2025

  • (Chappell E, Whorton J, Villafranca AA, Shahriari R, Brakenridge SC, Bennett JL, Ounpraseuth S, Ragan ED, Hogan WR, Bona J, Sexton KW, Brochhausen M.) Lecture Notes in Computer Science. 2026;16373 LNCS:1-8 SCOPUS ID: 2-s2.0-105026444934 01/01/2026

  • (Keshwani S, Smith KM, Winterstein AG, Gurka MJ, Walsh MG, Libby A, Hogan W, Pepine CJ, Cooper-DeHoff RM, Smith SM.) Am J Hypertens. 2025 Jul 15;38(8):560-569 PMID: 40259567 PMCID: PMC13010547 SCOPUS ID: 2-s2.0-105010929797 04/22/2025

  • (Sharma S, Nagar SD, Pemu P, Zuchner S, SEEC Consortium, Mariño-Ramírez L, Meller R, Jordan IK.) Nat Commun. 2025 May 03;16(1):4123 PMID: 40319026 PMCID: PMC12049439 SCOPUS ID: 2-s2.0-105004603467 05/04/2025

  • (Du X, Dobrowolski A, Brochhausen M, Garrett TJ, Hogan WR, Lemas DJ.) J Am Soc Mass Spectrom. 2025 Feb 05;36(2):433-438 PMID: 39755959 PMCID: PMC12711355 SCOPUS ID: 2-s2.0-85217085808 01/05/2025

  • (Li P, Spector E, Alkhuzam K, Patel R, Donahoo WT, Bost S, Lyu T, Wu Y, Hogan W, Prosperi M, Dixon BE, Dabelea D, Utidjian LH, Crume TL, Thorpe L, Liese AD, Schatz DA, Atkinson MA, Haller MJ, Shenkman EA, Guo Y, Bian J, Shao H.) Diabetes Obes Metab. 2025 Jan;27(1):102-110 PMID: 39344840 PMCID: PMC11620941 SCOPUS ID: 2-s2.0-85205514261 09/30/2024

  • (Nagarajan R, Kondo M, Salas F, Sezgin E, Yao Y, Klotzman V, Godambe SA, Khan N, Limon A, Stephenson G, Taraman S, Walton N, Ehwerhemuepha L, Pandit J, Pandita D, Weiss M, Golden C, Gold A, Henderson J, Shippy A, Celi LA, Hogan WR, Oermann EK, Sanger T, Martel S.) J Med Internet Res. 2024 Nov 14;26:e64226 PMID: 39541580 PMCID: PMC11605263 SCOPUS ID: 2-s2.0-85209360841 11/14/2024

  • (Duncan WD, Diller M, Dooley D, Hogan WR, Beverley J.) J Biomed Semantics. 2024 Aug 20;15(1):15 PMID: 39160586 PMCID: PMC11334599 SCOPUS ID: 2-s2.0-85201569755 08/20/2024

  • (Loftus TJ, Balch JA, Abbott KL, Hu D, Ruppert MM, Shickel B, Ozrazgat-Baslanti T, Efron PA, Tighe PJ, Hogan WR, Rashidi P, Cardel MI, Upchurch GR Jr, Bihorac A.) PLOS Digit Health. 2024 Aug;3(8):e0000561 PMID: 39178307 PMCID: PMC11343451 08/23/2024

  • (Mehta D, Whorton JM, Shahriari R, Ragan ED, Bona JP, Hogan WR, Sexton KW, Brochhausen M.) CEUR Workshop Proc. 2024 Jul;3939 PMID: 40196293 PMCID: PMC11973606 04/08/2025

  • (Loftus TJ, Ruppert MM, Shickel B, Ozrazgat-Baslanti T, Balch JA, Abbott KL, Hu D, Javed A, Madbak F, Guirgis F, Skarupa D, Efron PA, Tighe PJ, Hogan WR, Rashidi P, Upchurch GR Jr, Bihorac A.) Ann Surg Open. 2024 Jun;5(2):e429 PMID: 38911666 PMCID: PMC11191932 06/24/2024

  • (Hastings J, Zhang L, Schenk P, West R, Gehrke B, Hogan WR, Chorpita B, Johnston M, Marques MM, Webb TL, Baird HM, Crombez G, Michie S.) Wellcome Open Res. 2024;9:656 PMID: 39664869 PMCID: PMC11632217 12/12/2024

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