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Nisita Chaihongsa

Nisita Chaihongsa, PhD

Postdoctoral Researcher

Locations

  • Department of Physiology
  • HRC 4630

Contact Information

Education

PhD, Medical Physiology, Faculty of Medicine, Khon Kaen University, Thailand, 2023

MS, Medical Physiology, Faculty of Medicine, Khon Kaen University, Thailand, 2018

BS, Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand (Honors Program), 2016

Honors and Awards

2024 - new Investigator Awards Supported by the Council on Hypertension and the Council on Kidney in Cardiovascular Disease

2019-2023 - Scholarship, the Royal Golden Jubilee (RGJ) PhD Scholarship from the National Research Council of Thailand

2019 - Poster Presentation Award Winner at the 20th National Graduate Research Conference, Khon Kaen, Thailand

Research Interests

I obtained my MSc and PhD in medical physiology in Thailand. My graduate research contribution focused on essential hypertension-induced vascular dysfunction and remodeling. I investigated the effect of galangin (natural flavonoid) on blood pressure, vascular changes (impaired contraction and relaxation), sympathoexcitation (increased contractile responses to electrical field stimulation, the intensity of tyrosine hydroxylase and plasma norepinephrine), oxidative stress and inflammation. In addition, I expanded my research on renovascular hypertension-induced cardiorenal dysfunction by using a two-kidney one-clipped rat model. As a current postdoctoral researcher in Dr. Curt Sigmund’s Lab, my research provides important evidence for novel mechanisms of G-protein and -arrestin signaling specifically downstream of the AT1R in vascular smooth muscle cells. My research is focused on selective and inducible activation of the AT1R/Gq and AT1R/-arrestin pathways in regulating blood pressure and vascular function.