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Philip Mosier, PhD

Philip Mosier, PhD

Assistant Professor, Department of Biopharmaceutical Sciences

Locations

  • 黑料官网 School of Pharmacy
  • HRC 2708

Contact Information

Education

Postdoctoral training, Virginia Commonwealth University, 2004-2009
PhD, The Pennsylvania State University, State College, PA, 1998-2003
University of Nebraska Medical Center, Omaha, NE, 1992-1997
BS, Midland University, Fremont, NE, 1987-1992


Biography

Dr. Mosier graduated with a BS in Chemistry and Mathematics from Midland University, after which he studied medicinal chemistry at the University of Nebraska Medical Center. Following an industrial internship, he received his PhD in Chemistry from the Pennsylvania State University and pursued postdoctoral research in computational medicinal chemistry at Virginia Commonwealth University. He is an experienced educator who advocates for the importance of scientific literacy not only in health professions but also in general. His research is applicable to many therapeutic areas and focuses on understanding, through the use of computational tools, the structure of and mechanisms by which small molecules interact with and modulate the structure and function of their protein targets.

Research Interests

  • Molecular Modeling
  • Computer-Aided Drug Design (CADD)
  • Structural Biology
  • G Protein-Coupled Receptors (GPCRs)
  • Ligand-Gated Ion Channels (LGICs)
  • Tyrosine Kinase Inhibitors (TKIs)
  • Sigma Receptors
  • Neuroscience
  • Drugs of Abuse/Misuse
  • Natural Products
  • Infectious Diseases
  • Glycoscience
  • Hemostasis
  • Cancer

Publications

  • (Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C.) Eur J Med Chem. 2022 Jan 15;228:114038 PMID: 34902734 12/14/2021

  • (Niso M, Mosier PD, Marottoli R, Ferorelli S, Cassano G, Gasparre G, Leopoldo M, Berardi F, Abate C.) Future Med Chem. 2019 Oct;11(19):2547-2562 PMID: 31633399 10/22/2019

  • (Abdelkhalek AS, Alley GS, Alwassil OI, Khatri S, Mosier PD, Nyce HL, White MM, Schulte MK, Dukat M.) ACS Chem Neurosci. 2019 Mar 20;10(3):1380-1389 PMID: 30375852 10/31/2018

  • (Etobayeva I, Linden SB, Alem F, Harb L, Rizkalla L, Mosier PD, Johnson AA, Temple L, Hakami RM, Nelson DC.) Viruses. 2018 May 21;10(5) PMID: 29883383 PMCID: PMC5977269 06/09/2018

  • (Kent B, Raymond T, Mosier PD, Johnson AA, the 2016鈥�2017 VCU Phage Hunters.) Genome Announc. 2018 May 10;6(19) PMID: 29748396 PMCID: PMC5946042 05/12/2018

  • (Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL.) Cell. 2018 Jan 11;172(1-2):55-67.e15 PMID: 29307491 PMCID: PMC5802374 SCOPUS ID: 2-s2.0-85039900111 01/09/2018

  • (Chiang MJ, Musayev FN, Kosikova M, Lin Z, Gao Y, Mosier PD, Althufairi B, Ye Z, Zhou Q, Desai UR, Xie H, Safo MK.) Emerg Microbes Infect. 2017 Dec 06;6(12):e108 PMID: 29209052 PMCID: PMC5750462 12/07/2017

  • (Sankarayanarayanan NV, Strebel TR, Boothello RS, Sheerin K, Raghuraman A, Sallas F, Mosier PD, Watermeyer ND, Oscarson S, Desai UR.) Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2312-2317 PMID: 28124818 PMCID: PMC5347859 01/27/2017

  • (Alix K, Khatri S, Mosier PD, Casterlow S, Yan D, Nyce HL, White MM, Schulte MK, Dukat M.) ACS Chem Neurosci. 2016 Nov 16;7(11):1565-1574 PMID: 27533595 08/18/2016

  • (Sarkar A, Yu W, Desai UR, MacKerell AD, Mosier PD.) Glycobiology. 2016 Oct;26(10):1041-1047 PMID: 27496757 PMCID: PMC5072149 08/09/2016

  • (Mosier PD, Chiang MJ, Lin Z, Gao Y, Althufairi B, Zhou Q, Musayev F, Safo MK, Xie H, Desai UR.) Sci Rep. 2016 Aug 30;6:32340 PMID: 27573445 PMCID: PMC5004101 08/31/2016

  • (Joseph PR, Mosier PD, Desai UR, Rajarathnam K.) Biochem J. 2015 Nov 15;472(1):121-33 PMID: 26371375 PMCID: PMC4692082 09/16/2015

Publications of from the

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