Cerebellum Semaphore
What if deciphering a signaling system could help us understand how the brain controls balance, posture and complex movements such as playing a musical instrument? César Martinez, an MD/PhD student at Ϲ, is conducting research in the department of pharmacology and toxicology focused on the role of a set of biological transmitters and receivers – known as the endocannabinoid system – during the growth and development of the cerebellum, a region of the brain that contributes to the body’s ability to maintain balance and conduct precise, skillful movements.
The endocannabinoid system includes a number of signaling molecules, or endocannabinoids, that connect to and interact with specific cannabinoid protein receptors located in the brain, spinal cord and nerves spread throughout the body. The system also includes enzymes which control the levels of the signaling molecules. The amount of activity within this system influences numerous aspects of cognition and sensation, including appetite, pain and the learning of motor skills.
Studies have demonstrated that changes in endocannabinoid system signaling can affect the level of communication between nerve cells in the cerebellum that is critical to its ability to maintain balance and coordination. Cesar wor
The endocannabinoid system includes a number of signaling molecules, or endocannabinoids, that connect to and interact with specific cannabinoid protein receptors located in the brain, spinal cord and nerves spread throughout the body. The system also includes enzymes which control the levels of the signaling molecules. The amount of activity within this system influences numerous aspects of cognition and sensation, including appetite, pain and the learning of motor skills.
Studies have demonstrated that changes in endocannabinoid system signaling can affect the level of communication between nerve cells in the cerebellum that is critical to its ability to maintain balance and coordination. Cesar wor