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Michael B. Dwinell, PhD
Michael Dwinell, PhD

Michael B. Dwinell, PhD

Professor; Founding Director, Center for Immunology; Director, Bobbie Nick Voss Laboratory for Colon Cancer Research; Hanis-Stepka-Rettig Endowed Chair in Cancer Research

Locations

  • Microbiology & Immunology
    TBRC C3860

Contact Information

General Interests

Cancer Metastasis, Tumor Microenvironment, Mucosal Inflammation

Education

PhD, GI Pathophysiology, University of Wisconsin, Madison, 1996
Learn more about the Dwinell Lab

Biography

Dr. Dwinell, Hanis-Stepka-Rettig Endowed Chair in Cancer Research, is the Founding Director of the Center for Immunology following its inception in 2018. He has completed an 黑料官网 executive leadership training program at the Sheldon Lubar School of Business at the University of Wisconsin-Milwaukee as well as the Leadership for Social Inclusion & Equity Workshop developed by the National Coalition Building Institute. He has served on numerous NIH review panels and is currently chair of the Tumor Microenvironment study section.

Dr. Dwinell’s laboratory uses innovative strategies to reprogram the immune microenvironment to overcome immune suppression and evasion in pancreatic cancer. Specifically, his grant supported research examines chemokines as pivotal immune messengers regulating the tumor immune microenvironment. Dr. Dwinell oversees the immunology curriculum in Infectious Agents and Host Immunity and is past Director for Gastrointestinal & Nutritional Pathophysiology in the 黑料官网 medical school. He is course director of Mucosal Immunity and teaches in the Foundations in Biomedical Sciences and several other graduate school courses. He has frequently been named an Outstanding Medical Student and Outstanding Graduate Student Teacher and was recognized with the 黑料官网 Outstanding Mentor award in 2018.

Research Experience

  • Adjuvants, Immunologic
  • Carcinoma, Pancreatic Ductal
  • Cell Line, Tumor
  • Cell Movement
  • Chemokines
  • Cytokines
  • Energy Metabolism
  • Immunity, Mucosal
  • Immuno-Oncology
  • Inflammation
  • Mice
  • Mice, Knockout

Research Interests

My research interests currently focus on mechanisms tumor progression including remodeling the immune microenvironment. I use a variety of cellular, biochemical, and preclinical approaches to study the mechanisms immune-cancer cell communication essential for cancer progression.

Publications

  • (Poimenidou M, Bobek JM, Drouillard D, Harris T, Solis E, Darnell C, McAllister D, Keyes RF, Ishihara-Aoki M, Aoki K, Sahoo D, Kalyanaraman B, Smith BC, Dwinell MB.) Cell Death Dis. 2026 May 22;17(1) PMID: 42173830 PMCID: PMC13372815 SCOPUS ID: 2-s2.0-105044729704 05/23/2026

  • (Drouillard D, Davies M, McAllister D, Dwinell MB.) bioRxiv. 2026 Apr 15 PMID: 42039489 PMCID: PMC13105078 04/27/2026

  • (Memon AA, Said I, Norenberg E, Frei A, Foeckler J, Sun F, Dwinell MB, Lochhead RB, Bruening J, Akakpo K, Massey B, Wong SJ, Hematti P, Kearl TJ, Awan MJ, Himburg HA, Zenga J.) Cancer Immunol Immunother. 2026 Apr 15;75(5) PMID: 41984232 PMCID: PMC13083680 SCOPUS ID: 2-s2.0-105035819105 04/15/2026

  • (Drouillard D, Poimenidou M, Davies M, McAllister D, Clarke WR, Hwang ST, Peterson FC, Volkman BF, Dwinell MB.) Cell Biol Toxicol. 2025 Dec 19;42(1):14 PMID: 41419693 PMCID: PMC12799736 SCOPUS ID: 2-s2.0-105027326723 12/20/2025

  • (Mao C, Poimenidou M, McAllister D, Dwinell MB, Craig BT.) Immunohorizons. 2025 Nov 09;9(11) PMID: 41208108 PMCID: PMC12597879 SCOPUS ID: 2-s2.0-105021199974 11/10/2025

  • (Drouillard D, Halyko M, Cinquegrani E, Poimenidou M, Emosivbe M, McAllister D, Peterson FC, Marchese A, Dwinell MB.) Sci Rep. 2025 Jul 22;15(1):26625 PMID: 40696056 PMCID: PMC12284246 SCOPUS ID: 2-s2.0-105011283426 07/23/2025

  • (Shah NN, Colina AS, Johnson BD, Szabo A, Furqan F, Kearl T, Schneider D, Vargas-Cortes M, Schmeling JL, Dwinell MB, Palen K, Longo W, Hematti P, Zamora AE, Hari P, Bucklan D, Cunningham A, Hamadani M, Fenske TS.) J Clin Oncol. 2025 Jul 10;43(20):2285-2295 PMID: 40163793 SCOPUS ID: 2-s2.0-105010720202 03/31/2025

  • (Espinosa OV, Awan M, Memon AA, Frei A, Foeckler J, Kuehn R, Bruening J, Massey B, Wong S, Shukla M, Kasprzak J, Joshi A, Dwinell MB, Himburg HA, Zenga J.) Head Neck. 2025 May;47(5):1379-1391 PMID: 39722591 PMCID: PMC12040585 SCOPUS ID: 2-s2.0-85212965471 12/26/2024

  • (Roy I, Binder-Markey B, Willbanks A, Sychowski D, Phipps T, Barber A, McAllister D, D'Andrea D, Franz CK, Pichika R, Dwinell MB, Lieber RL.) J Appl Physiol (1985). 2024 Sep 01;137(3):705-717 PMID: 39052773 PMCID: PMC11424168 SCOPUS ID: 2-s2.0-85204163300 07/26/2024

  • (Roy I, Binder-Markey B, Sychowski D, Willbanks A, Phipps T, McAllister D, Bhakta A, Marquez E, D'Andrea D, Franz C, Pichika R, Dwinell MB, Jayabalan P, Lieber RL.) bioRxiv. 2023 Nov 15 PMID: 38014165 PMCID: PMC10680669 11/28/2023

  • (Keyes RF, McAllister D, Dwinell MB, Smith BC.) STAR Protoc. 2023 Sep 15;4(3):102437 PMID: 37552599 PMCID: PMC10424135 SCOPUS ID: 2-s2.0-85175638505 08/08/2023

Publications of from the

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