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Kindel Research Laboratory

Location: Children's Research Institute 4388

Mission Statement

Dr. Tammy Kindel in the lab.Develop novel surgical and non-surgical therapies for metabolic diseases of obesity based on mechanistic investigations of bariatric surgery.

Tammy Kindel, MD, PhD, FACS, FASMBS
Professor, Division of Minimally Invasive & Gastrointestinal Surgery
Medical Director, Bariatric Surgery Program
Froedtert Hospital and the Ϲ
(414) 955-1763
tkindel@mcw.edu

Research Summary

The goal of Dr. Kindel’s laboratory is to develop an understanding for the improvement in metabolic and cardiovascular diseases after bariatric surgery. Using animal models of obesity and metabolic disease, the Kindel laboratory performs rodent bariatric surgery studying various mechanisms including the gut microbiome, bile acid signaling, blood-based secretory factors, and gut hormones. The Kindel laboratory also utilizes cell culture models of cardiac stress to understand the relationship between circulating blood factors and cardioprotection after bariatric surgery. Further, the Kindel laboratory utilizes clinical samples and patient outcomes whenever possible to confirm benchtop findings with the goal of ultimately developing novel therapies for metabolic disease to trial within patients. If interested in collaborating or learning more about the Kindel laboratory, please contact Dr. Tammy Kindel.

Funding Support

  • Michael Keelan Jr. MD Research Foundation Award, Ϲ CVRC
  • Research Affairs Committee
  • American College of Surgeons George Clowes Career Development Award
  • NIH/NHLBI K08 Career Development Award- K08 HL140000-01A1

Lab Members

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Tammy Lyn Kindel, MD, PhD, FACS, FASMBS

Professor; Director, Bariatric Surgery Program

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Andrew Kim, MD

Boston University School of Medicine

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Matt Barron

Research Scientist I